artemisinin

Noun

artemisinin (countable and uncountable, plural artemisinins)

1. An antimalarial drug derived from the sweet wormwood shrub, Artemisia annua, found as the active ingredient in traditional Chinese medical herbal treatment for malaria, chemically a sesquiterpene lactone - C₁₅H₂₂O₅.
   • Artemisinin (Qinghaosu) isolated from Artemisia annua is a novel sesquiterpene lactone bearing an unusual endoperoxide function.1994 May, Mankil Jung, “Current Developments in the Chemistry of Artemisinin and Related Compounds”, in Current Medicinal Chemistry, page 35
   • The practical value of artemisinin itself as a therapeutic agent has been limited by several factors, however. Artemisinin has a high rate of recrudescence [8], poor oral activity [8], a short half-life in plasma [9], and limited solubility in both water and oil [10].1998, Dee Ann Casteel, “Synthesis of Simple Bridged Bicyclic Trioxanes as Analogs of the Antimalarial Natural Product, Atemisinin”, in Attaur Rahman, editor, New Trends in Natural Product, page 30

   Synonyms:

   qinghaosu