Word.ws English Dictionary

binimetinib

Syllables: bi·ni·me·ti·nibUK/bɪnɪˈmɛtɪnɪb//bɪnɪˈmɛtɪnɪb/

binimetinib noun: a drug with the molecular formula C₁₇H₁₅BrF₂N₄O₃ that inhibits mitogen-activated protein kinase kinase (MEK), and is approved for use in combination with encorafenib to treat certain melanomas.

binimetinib: a drug with the molecular formula C₁₇H₁₅BrF₂N₄O₃ that inhibits mitogen-activated protein kinase...
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Noun

binimetinib (uncountable)

  1. A drug with the molecular formula C₁₇H₁₅BrF₂N₄O₃ that inhibits mitogen-activated protein kinase kinase (MEK), and is approved for use in combination with encorafenib to treat certain melanomas.
    • Binimetinib (MEK162; ARRY-438162) is a potent, adenosine triphosphate-uncompetitive, highly selective allosteric inhibitor of MEK1/2 with demonstrated on-target activity in vitro and in vivo, including models of cancer [...] In vivo, binimetinib displays broad anti-tumour activity in xenograft...2017 February 28, Johanna C. Bendell et al., “A Phase 1 Dose-escalation and Expansion Study of Binimetinib (MEK162), a Potent and Selective Oral MEK1/2 Inhibitor”, in British Journal of Cancer...
    • Binimetinib improved progression-free survival compared with dacarbazine and was tolerable. Binimetinib might represent a new treatment option for patients with NRAS-mutant melanoma after failure of immunotherapy.2017 April 1, Reinhard Dummer et al., “Binimetinib versus Dacarbazine in Patients with Advanced NRAS-mutant Melanoma (NEMO): A Multicentre, Open-label, Randomised, Phase 3 Trial”, in David...

Examples of binimetinib in a sentence

  • These non-clinical data support the use of binimetinib in a wide variety of tumour types, with a priority in tumours with aberrantly activated MAPK pathway signalling.2017 February 28, Johanna C. Bendell et al., “A Phase 1 Dose-escalation and Expansion Study of Binimetinib (MEK162), a Potent and Selective...
  • Monitor patients for an increased risk of new primary cancers, both cutaneous and non-cutaneous, while on therapy and for up to 6 months following the last dose of binimetinib. [...] 10.2020, Edward Chu; Vincent T[heodore] DeVita, Jr., “Chemotherapeutic and Biologic Drugs”, in Physicians’ Cancer Chemotherapy Drug Manual...

Origin of binimetinib

From bini- (a unique prefix) + -metinib (suffix indicating an inhibitor of mitogen-activated protein kinase kinase (MEK)).

Questions about binimetinib

What does binimetinib mean?
Binimetinib means a drug with the molecular formula C₁₇H₁₅BrF₂N₄O₃ that inhibits mitogen-activated protein kinase kinase (MEK), and is approved for use in combination with encorafenib to treat certain melanomas.
How do you use binimetinib in a sentence?
These non-clinical data support the use of binimetinib in a wide variety of tumour types, with a priority in tumours with aberrantly activated MAPK pathway signalling.
What part of speech is binimetinib?
Binimetinib is a noun.
How do you pronounce binimetinib?
Binimetinib is pronounced /bɪnɪˈmɛtɪnɪb/ (UK).

Words near binimetinib in the dictionary

  1. Bini
  2. Binidayan
  3. binifibrate
  4. Binigura
  5. Biniguy
  6. binimetinib
  7. biniodide
  8. biniodides
  9. Binion
  10. Binions
  11. biniou

Source and license

Adapted from Wiktionary: binimetinib (page history and authors). Text available under the Creative Commons Attribution-ShareAlike 4.0 license. Word.ws reformatted the entry and added links. Wiktionary data of 2026-09-02.

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Pronunciation audio from Wikimedia Commons, each file under its own free license: En-us-binimetinib.oga.

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