Word.ws English Dictionary

downsies

downsies noun: synonym of tranquilizers (“drugs used to reduce anxiety or tension”).

Noun

downsies pl (plural only)

  1. (plural, plural-only, rare, slang) Synonym of tranquilizers (“drugs used to reduce anxiety or tension”).
    • The Rolling Stones cut a record called “Mother’s Little Helpers.’[’] An innocuous title? You bet it was, but the lyrics revealed that “Mother’s Little Helpers” are the “upsies and downsies” that mom takes to get her through the day. The “upsies” are the pep pills she takes when she wakes up and the...1969 March 11, Ed Zuckerman, quotee, Congressional Record: Proceedings and Debates of the 91ˢᵗ Congress, First Session, volume 115, part 5, Washington, D.C.: United States Government Printing Office...
    • Sylvia may not take drugs, but Kim was very into pills—upsies and downsies and in-betweensies.1971, David Freeman, “Sylvia the Hooker”, in U. S. Grant in the City and Other True Stories of Jugglers and Pluggers, Swatters and Whores, New York, N.Y.: Viking Press, →ISBN, page 46
    Synonyms:
    tranquilizers

Examples of downsies in a sentence

  • You bet it was, but the lyrics revealed that “Mother’s Little Helpers” are the “upsies and downsies” that mom takes to get her through the day.1969 March 11, Ed Zuckerman, quotee, Congressional Record: Proceedings and Debates of the 91ˢᵗ Congress, First Session, volume 115, part 5...
  • Girls seek release through drinking and pills and dexies and upsies and downsies.1973, Susan Hall, “Individual Entrepreneurs”, in Ladies of the Night (A Prairie House Book), New York, N.Y.: Trident Press, →LCCN, →OCLC...
  • I must still not be awake. […] If the girls had been doing downsies in this tiny little compartment, they should have put us all to sleep.1989 May, Cynthia Felice, Connie Willis, chapter 14, in Light Raid, New York, N.Y.: Ace Books, →ISBN, pages 150–151:

Synonyms of downsies

Origin of downsies

From down + -sies.

Questions about downsies

What does downsies mean?
Downsies means synonym of tranquilizers (“drugs used to reduce anxiety or tension”).
How do you use downsies in a sentence?
You bet it was, but the lyrics revealed that “Mother’s Little Helpers” are the “upsies and downsies” that mom takes to get her through the day.
What part of speech is downsies?
Downsies is a noun.

Words near downsies in the dictionary

  1. downside
  2. downside beta
  3. downside betas
  4. downside up
  5. downsides
  6. downsies
  7. downsitting
  8. downsittings
  9. downsizable
  10. downsize
  11. downsized

Source and license

Adapted from Wiktionary: downsies (page history and authors). Text available under the Creative Commons Attribution-ShareAlike 4.0 license. Word.ws reformatted the entry and added links. Wiktionary data of 2026-09-02.

Last updated:

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