hypercondensations

Noun

hypercondensation (countable and uncountable, plural hypercondensations)

1. A class of condensation reaction involving reaction of a carbonyl group with a methylene group to form an alkene with the loss of the elements of water (>C=O + CH₂< -> >C=C<).
2. The severe compaction of chromosomes.
   • In addition, PNAP - 6h decreased CDK1 and cyclin B1 expression, most likely leading to G 2 /M arrest, and induced morphological changes, such as nuclear shrinkage, nuclear fragmentation, and nuclear hypercondensation, as observed by Hoechst 33342 staining.2015 October 23, “Structure-Activity Relationship of Synthetic 2-Phenylnaphthalenes with Hydroxyl Groups that Inhibit Proliferation and Induce Apoptosis of MCF-7 Cancer Cells”, in PLOS ONE, →DOI