knockins

Noun

knockin (plural knockins)

1. The insertion of a cDNA sequence at a particular locus in an organism's chromosome
   • The advantage of this design is that the targeted knockin retains the intact endogenous aggrecan locus and expresses the tamoxifen-inducible CreERT2 protein from a second IRES-driven open reading frame.2015 July 8, “Non-Invasive Quantification of Cartilage Using a Novel In Vivo Bioluminescent Reporter Mouse”, in PLOS ONE, →DOI

See all 2 meanings of knockin