Word.ws English Dictionary

misfold

/mɪsˈfoʊld/

misfold verb: to fold into an unusual or incorrect tertiary structure; misfolded proteins occur in various diseases, including amyloidoses and dementias, although the question of causation versus consequence is not yet definitively answered for dementias.

Verb

misfold (third-person singular simple present misfolds, present participle misfolding, simple past and past participle misfolded)

  1. (intransitive) To fold into an unusual or incorrect tertiary structure; misfolded proteins occur in various diseases, including amyloidoses and dementias, although the question of causation versus consequence is not yet definitively answered for dementias.
    • The prionopathies are best known among the neurodegenerative diseases for their ability to misfold, self-propagate, and infect other organisms.2021 March 1, Anderson, K.N.; Overcast, W.B.; Brosch, J.R.; Graner, B.D.; Veronesi, M.C., “Prionopathies and Prionlike Protein Aberrations in Neurodegenerative Diseases”, in American Society of...

Noun

IPA/ˈmɪsfoʊld/

misfold (plural misfolds)

  1. An incorrect or abnormal folding.

Forms of misfold

Verb
third-person singular presentmisfolds
present participlemisfolding
past participlemisfolded
pastmisfolded
Noun
pluralmisfolds

Origin of misfold

From mis- + fold.

Words that rhyme with misfold

30 more rhymesFewer rhymes

Questions about misfold

What does misfold mean?
Misfold means to fold into an unusual or incorrect tertiary structure; misfolded proteins occur in various diseases, including amyloidoses and dementias, although the question of causation versus consequence is not yet definitively answered for dementias.
What part of speech is misfold?
Misfold can be a verb or a noun.
How do you pronounce misfold?
Misfold is pronounced /mɪsˈfoʊld/.
What is the past tense of misfold?
The past tense of misfold is misfolded.

Words near misfold in the dictionary

  1. misfocused
  2. misfocuses
  3. misfocusing
  4. misfocussed
  5. misfocussing
  6. misfold
  7. misfolded
  8. misfolding
  9. misfoldings
  10. misfolds
  11. misfool

Source and license

Adapted from Wiktionary: misfold (page history and authors). Text available under the Creative Commons Attribution-ShareAlike 4.0 license. Word.ws reformatted the entry and added links. Wiktionary data of 2026-09-02.

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