premutation
premutation adjective: of or relating to a premutation.
Adjective
premutation (not comparable)
- Of or relating to a premutation.
- Fragile X syndrome is caused by mutations in the FMR1-gene, which is characterized by an expansion of a CGG triplet in the 5’ UTR. Normal individuals have 6–44 CGG repeats, while carriers of gray zone or premutation alleles have 45–54 and 55–200 repeats, respectively.2015 July 30, “Positron Emission Tomography (PET) Quantification of GABA A Receptors in the Brain of Fragile X Patients”, in PLOS ONE, →DOI
Noun
premutation (plural premutations)
- A nucleotide sequence variation that is not enough to be classed as a mutation (for example, does not affect protein expression enough to produce clinical symptoms) but nonetheless represents an unusual variant that is predisposed to still greater variation in future cell divisions (that is, predisposed to leading to a mutation).
Forms of premutation
| plural | premutations |
|---|
Origin of premutation
From pre- + mutation.
Questions about premutation
- What does premutation mean?
- Premutation means of or relating to a premutation.
- What part of speech is premutation?
- Premutation can be an adjective or a noun.
Words near premutation in the dictionary
Source and license
Adapted from Wiktionary: premutation (page history and authors). Text available under the Creative Commons Attribution-ShareAlike 4.0 license. Word.ws reformatted the entry and added links. Wiktionary data of 2026-09-02.
Last updated:
Cite this entry: “premutation.” Word.ws, https://word.ws/premutation. Based on Wiktionary, CC BY-SA 4.0.
