PSSD
PSSD is the initialism of post-SSRI sexual dysfunction.
PSSD is the initialism of portable SSD.
Meaning of post-SSRI sexual dysfunction
Noun
post-SSRI sexual dysfunction (uncountable, abbreviation PSSD)
- A permanent condition of physical and psychological sexual anhedonia, among other symptoms, that occurs in around 1 in 200 people who have consumed SRI drugs (SSRIs, SNRIs, etcetera), which is caused by the permanent desensitization of some serotonin receptors.
- I've since discovered this side-effect isn't uncommon and has a name: PSSD (post-SSRI sexual dysfunction). I know men who also suffer with PSSD and struggle with the same genital numbness and anorgasmia, coupled with erectile dysfunction.[2018 June 8, anonymous author, “My life in sex: ‘After taking antidepressants, my genitals felt numb’”, in The Guardian
- Synonyms:
- PSSD, post-SSRI syndrome
Forms of PSSD
| plural | PSSDs |
|---|
Questions about PSSD
- What is PSSD the initialism of?
- PSSD is the initialism of post-SSRI sexual dysfunction.
Words near PSSD in the dictionary
Source and license
Adapted from Wiktionary: PSSD (page history and authors); post-SSRI sexual dysfunction (page history and authors). Text available under the Creative Commons Attribution-ShareAlike 4.0 license. Word.ws reformatted the entry and added links. Wiktionary data of 2026-09-02.
Last updated:
Cite this entry: “PSSD.” Word.ws, https://word.ws/pssd. Based on Wiktionary, CC BY-SA 4.0.