rapalogues

Noun

rapalogue (plural rapalogues)

1. Any of several synthetic drugs that are analogues of rapamycin
   • However, despite initially promising preclinical and clinical data in renal cell carcinoma, studies now suggest that as single agents, the activity of rapalogues is modest and sporadic in other solid tumors.2015 August 6, Tracey R. O’Donovan et al., “Lithium Modulates Autophagy in Esophageal and Colorectal Cancer Cells and Enhances the Efficacy of Therapeutic Agents In Vitro and In Vivo”, in PLoS ONE...