ritlecitinib

Noun

ritlecitinib (uncountable)

1. A medication belonging to the class of Tec/Janus kinase inhibitors, used for the treatment of alopecia areata.
   • Ritlecitinib is an irreversible covalent inhibitor that binds to a distinct cysteine residue in the JAK3 catalytic domain, which other JAK family members lack. […] Ritlecitinib was found to be superior to placebo in a phase II study in RA patients with an inadequate response to MTX (76).2021 December, Christine Liu, Jacqueline Kieltyka, Roy Fleischmann, Massimo Gadina, John J. O’Shea, “A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?”, in Arthritis &...