Word.ws English Dictionary

RO5

RO5 is the abbreviation of Lipinski's rule of five.

Meaning of Lipinski's rule of five

Proper noun

Lipinski's rule of five

  1. A rule of thumb stating that a chemical compound is likely to be an orally active drug in humans unless it violates more than one of these criteria: (i) no more than 5 hydrogen bond donors (the total number of nitrogen–hydrogen and oxygen–hydrogen bonds); (ii) no more than 10 hydrogen bond acceptors (all nitrogen or oxygen atoms); (iii) a molecular mass less than 500 daltons; (iv) an octanol-water partition coefficient (log P) that does not exceed 5.

Questions about RO5

What is RO5 the abbreviation of?
RO5 is the abbreviation of Lipinski's rule of five.

Words near RO5 in the dictionary

  1. RO
  2. Ro-Henu
  3. ro-ro
  4. ro-ros
  5. ro.
  6. RO5
  7. Roa
  8. Roa Island
  9. roach
  10. roach bomb
  11. roach bombs

Source and license

Adapted from Wiktionary: RO5 (page history and authors); Lipinski's rule of five (page history and authors). Text available under the Creative Commons Attribution-ShareAlike 4.0 license. Word.ws reformatted the entry and added links. Wiktionary data of 2026-09-02.

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Cite this entry: “RO5.” Word.ws, https://word.ws/ro5. Based on Wiktionary, CC BY-SA 4.0.