upadacitinib

Noun

upadacitinib (uncountable)

1. A medication belonging to the class of Janus kinase inhibitors, used for the treatment of several immune-mediated diseases such as rheumatoid arthritis, ankylosing spondylitis, and atopic dermatitis.
   • Upadacitinib monotherapy has also been shown to be more effective than MTX in MTX-naive patients with RA (24). Both upadacitinib and filgotinib have been referred to as “second-generation jakinibs” since they both preferentially inhibit JAK1 in vitro but their clinical efficacy and safety, to a...2021 December, Christine Liu, Jacqueline Kieltyka, Roy Fleischmann, Massimo Gadina, John J. O’Shea, “A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?”, in Arthritis &...