12-Letter Words Starting with D
There are 277 twelve-letter words that start with D on Word.ws, from dactinomycin to dysmenorrhea. The most common are distribution, disappointed, developments, difficulties and deliberately.
Meanings from Wiktionary. Not an official Scrabble, Words With Friends or Wordle word list.
All 277 twelve-letter words that start with D
DA
- dactinomycin22n. Actinomycin D.
- daunorubicin17n. A synthetic anthracycline antibiotic C₂₇H₂₉NO₁₀ which is a nitrogenous...
DE
- deactivation18n. The act of deactivating something, such as a bomb or alarm.
- deallocation15n. The act of deallocating.
- deathstalker20n. Leiurus quinquestriatus, an extremely venomous scorpion of the family...
- debaucherous20adj. Excessively indulgent in sensual pleasures.
- debilitating16adj. Causing a loss of energy or strength.
- debilitation15n. The act or process of debilitating, or the condition of one who is...
- decalcomania19n. The process of transferring decorative designs onto surfaces using...
- decapitation17n. Beheading; the act of beheading or decapitating.
- deceleration15n. The act or process of decelerating.
- decentralise15v. To cause something to change from being concentrated at one point to...
- decentralize24v. To cause to change from being concentrated at one point or site to...
- decidability21n. The state or condition of being decidable.
- decipherable22adj. That can be deciphered, understood or comprehended.
- decipherment22n. The analysis of documents written in ancient languages, where the...
- decisiveness18n. The state or quality of being decisive.
- deckbuilding23n. The construction of a deck of playing cards in certain games where...
- decluttering16n. The act or process of removing clutter; tidying, removing unwanted or...
- decommission19v. To take out of service or to render unusable.
- decomposable21adj. Able to be decomposed.
- decompressor19n. That which decompresses.
- decongestant16n. A drug that relieves congestion, e.g. pseudoephedrine.
- decongestion16n. The process of decongesting something.
- deconversion18n. Undoing or dissolution of conversion.
- decoratively21adv. In a decorative manner.
- decorticated18adj. Having had the cortex removed.
- decreasingly19adv. In a decreasing manner; progressively less.
- defenestrate16v. To eject or throw (someone or something) from or through a window.
- deferoxamine25n. A siderophore, produced by the actinobacterium Streptomyces pilosus...
- defibrillate18v. To stop the fibrillation of the heart in order to restore normal...
- definability21n. The quality of being definable.
- definiteness16n. The state or quality of being definite.
- definitional16adj. Of or relating to a definition.
- definitively22adv. In a way that is not only decisive, but also conclusive and final.
- deflagration17n. The act of deflagrating; an intense fire; a conflagration or explosion....
- deflationary19adj. Associated with or tending to cause deflation.
- defragmenter19n. That which defragments; a program that performs defragmentation.
- degeneration14n. The process or state of growing worse, or the state of having become...
- degenerative17adj. Characterized by or causing degeneration.
- deglaciation16n. The removal of all glacial land ice from a region, usually by melting.
- dehumanising19adj. Causing dehumanization.
- dehumanizing28n. An act of dehumanization.
- dehumidifier22n. A device for removing the moisture content from air.
- deionization22n. The use of ion exchange to remove ionic substances from a solution.
- delamination15n. The separation of the layers of a laminar composite material as a...
- delegitimize25v. To make something less legitimate.
- deleveraging18n. The process of something being deleveraged.
- deliberately18adv. Intentionally, or after deliberation; not accidentally.
- deliberation15n. The act of deliberating, or of weighing and examining the reasons for...
- deliberative18adj. That deliberates, considers carefully.
- delicatessen15n. A shop that sells cooked or prepared foods ready for serving.
- delightfully23adv. In a delightful manner.
- delimitation15n. The act of delimiting something.
- deliquescent24adj. Seeming to melt away.
- deltamethrin18n. A pyrethroid insecticide.
- delusionally16adv. In a delusional way.
- demagnetized26adj. From which all magnetism has been removed.
- demethylated22adj. That has been subjected to demethylation.
- demilitarize24v. To remove troops from (an area).
- demodulation16n. The inverse of the effect of modulation, or applying a signal to a...
- demographics23n. The characteristics of human populations for purposes of social studies.
- demonization24n. The act of demonizing.
- demonologist16n. An expert in the study of demonology.
- demonstrable17adj. Able to be demonstrated.
- demonstrably20adv. In such a manner that is capable of being demonstrated, shown, or...
- demonstrator15n. One who demonstrates anything, or proves beyond doubt.
- demoralizing25adj. Disheartening.
- demotivating19adj. That causes demotivation.
- demotivation18n. A feeling or state of being demotivated.
- denaturation13n. The deliberate addition of a noxious substance to alcohol to make it...
- denomination15n. The act of naming or designating.
- denotational13adj. Of or pertaining to denotation.
- denouncement17n. An act of denouncing; a denunciation.
- densitometer15n. A device that measures the optical density of a material; especially to...
- densitometry18n. The measurement of optical density by use of a densitometer.
- denticulated16adj. Denticulate, having many small toothlike protrusions.
- denuclearize24v. To ban, remove or reduce the numbers of nuclear weapons in an area.
- denunciation15n. Proclamation; announcement; a publishing.
- deoxycholate28n. Any salt or ester of deoxycholic acid.
- deoxygenated25adj. Containing no or reduced oxygen.
- deoxyglucose26n. A deoxy sugar derived from glucose.
- deoxyuridine24n. A deoxyribonucleoside related to uridine.
- departmental17adj. Of or relating to a department.
- depoliticize26v. To remove something from political influence.
- depopulation17n. The act of depopulating or condition of being depopulated; the...
- depositional15adj. Of, pertaining to, or in the nature of a deposit or a deposition.
- depreciating18adj. That is declining in value.
- depreciation17n. The state of being depreciated; disparagement.
- depressingly19adv. In a depressing manner.
- depressurize24v. To reduce the air pressure within a chamber.
- deprogrammer20n. One who deprograms.
- deprotection17n. The removal of a protecting group.
- deprotonated16adj. That has had one or more protons removed.
- deregulation14n. The process of removing constraints, especially government-imposed...
- deregulatory17adj. Of or pertaining to deregulation.
- derivational16adj. Of or pertaining to derivation; relating to that which is derived.
- derivatively22adv. In a derivative fashion.
- dermabrasion17n. A cosmetic medical procedure in which the surface of the epidermis of...
- dermatologic18adj. Dermatological.
- dermatophyte23n. Microsporum species.
- derogatorily17adv. In a derogatory manner.
- desalination13n. The process of removing salt from sea water in order to make drinking...
- desaturation13n. The conversion of a saturated compound to an unsaturated one by...
- desensitized23adj. Not sensitized.
- desiderative17adj. Having or indicating wish or desire.
- desirability18n. The state of being desirable.
- desmoplastic19adj. That produces adhesions.
- desmopressin17n. A synthetic replacement for vasopressin.
- despairingly19adv. In a despairing manner.
- despitefully21adv. In a despiteful manner; spitefully.
- despoliation15n. A stripping or plundering; spoliation.
- despondently19adv. In a despondent manner.
- despotically20adv. In a despotic manner.
- desquamation24n. The shedding of the outer layers of the skin.
- destigmatize25v. To remove the disgraceful or ignominious characterization; to remove...
- destructible17adj. Liable to destruction; capable of being destroyed.
- determinable17adj. Able to be determined or limited.
- determinedly19adv. In a determined manner.
- dethronement18n. Removal from a superior place in a hierarchy.
- detribalized25adj. Detached from one's tribe, or from tribal traditions.
- developments20n. A group of building complexes or apartments. Often used for low income...
- dextrocardia23n. A congenital abnormality in which the heart is transposed to the right...
DI
- diabolically20adv. In a diabolical manner.
- diagrammatic20adj. In the form of a diagram.
- dialectician17n. Someone skilled in dialectics: someone able to arrive at logical...
- dialectology19n. The study of dialects.
- diamagnetism18n. A weak form of magnetism that is only observed in the presence of an...
- diatomaceous17adj. Of, pertaining to, or containing diatoms or their coverings.
- diazomethane27n. The simplest diazo compound, CH₂=N⁺=N⁻; a toxic, yellow, explosive gas...
- dicarboxylic29adj. Having two carboxylic groups.
- dichotomized30adj. Divided into dichotomous parts.
- dictatorship20n. A type of government where absolute sovereignty is allotted to an...
- didactically21adv. In a didactic manner.
- diencephalon20n. The region of the human brain, specifically the human forebrain, that...
- diethylamide22n. The derivative of a compound formed by adding an amide group with two...
- diethylamino21n. The univalent radical (CH₃CH₂)₂N- derived from diethylamine.
- differencing22adj. Involving the taking of differences or noting of changes.
- differential19adj. Of or pertaining to a difference.
- difficulties21n. A series of frustrations.
- digitization23n. The conversion of data or information from analog to digital or binary.
- diisocyanate18n. Any compound containing two isocyanate anions or functional groups, but...
- dilapidation16n. The state of being dilapidated, reduced to decay, partially ruined.
- dilettantism15n. The act of behaving like a dilettante, of being an amateur or dabbler...
- dimerization24n. Any chemical reaction in which two monomers react to form a dimer.
- diminishment20n. The act of diminishing; reducing in size, quantity, or quality.
- dinucleotide16n. Any molecule consisting primarily of two nucleotide units.
- diphtheritic23adj. Resembling or related to diphtheria.
- dipropionate17n. Any salt or ester containing two propionate groups.
- dipyridamole21n. A drug that inhibits thrombus formation when given chronically and...
- directedness16n. The state or quality of being directed.
- directorship20n. The office of a director.
- disaccharide21n. Any sugar, such as sucrose, maltose and lactose, consisting of two...
- disadvantage18n. A weakness or undesirable characteristic; con; drawback.
- disaffection21n. Discontent; unrest.
- disaffiliate19v. To cease to have an affiliation (with); to take steps to break an...
- disaggregate16adj. Not aggregate.
- disagreeable16adj. Causing repugnance; unpleasant to the feelings or senses; displeasing.
- disagreeably19adv. In a disagreeable manner.
- disagreement16n. An argument or debate.
- disallowance18n. The action of not allowing, or of withdrawing allowance.
- disambiguate18v. To remove ambiguities from; to make less ambiguous; to clarify or...
- disappearing18n. Disappearance.
- disappointed18adj. Defeated of expectations or hope; experiencing disappointment; let down.
- disapproving21adj. Expressing or conveying disapproval.
- disassembler17n. A computer program that examines another computer program and attempts...
- disassociate15v. To separate (oneself); to dissolve one's association with a person...
- disastrously16adv. In a disastrous way. (Of the nature of a disaster; calamitously.).
- disbelieving19adj. Refusing to believe; skeptical or incredulous.
- discerningly19adv. In a discerning manner.
- discipleship22n. The condition of being a disciple.
- disciplinary20adj. Having to do with discipline, or with the imposition of discipline.
- disciplining18n. The use of punishment to compel behavior.
- discolouring16n. Discoloration.
- discomfiting21adj. Tending to discomfit (“embarrass greatly; upset the composure of...
- discomfiture20n. An emotional state similar to that arising from defeat; frustration...
- disconcerted18adj. Ruffled; upset and embarrassed.
- disconnected18adj. That is no longer connected.
- disconnector17n. A switching device used to open an electric circuit when there is no...
- disconsolate15adj. Cheerless, dreary.
- discontented16adj. Experiencing discontent, dissatisfaction.
- discontinued16adj. Permanently no longer available for sale.
- discordantly19adv. In a discordant manner.
- discouraging17adj. That causes discouragement.
- discourteous15adj. Impolite; lacking consideration for others.
- discoverable20adj. Able to be discovered.
- discrediting17n. The act by which something is discredited.
- discreteness15n. The state or quality of being discrete, separated or distinct.
- discriminant17n. An expression that gives information about the roots of a polynomial...
- discriminate17v. To make distinctions.
- discursively21adv. In a discursive manner.
- disdainfully20adv. In a disdainful manner.
- disembarking22n. A disembarkation.
- disenchanted19adj. Disappointed; having lost belief or enthusiasm through bad experience.
- disestablish18v. To deprive (an established church, military squadron, operations base...
- disfranchise21v. To deprive someone of some privilege, especially the right to vote; to...
- disgorgement17n. An act of disgorging (giving something up involuntarily).
- disgustingly18adv. In a disgusting manner.
- disheartened17adj. Discouraged, despairing.
- dishonorable18adj. Without honor, or causing dishonor.
- dishonorably21adv. In a dishonorable manner.
- disincentive18n. That which discourages a particular behaviour; a deterrent.
- disinfectant18adj. Serving to kill germs or viruses.
- disinfection18n. Treatment with disinfectant materials in order to destroy harmful...
- disinflation16n. A decrease in the inflation rate.
- disingenuous14adj. Not honourable; unworthy of honour.
- disintegrate14v. To undo the integrity of; to break into parts.
- disinterment15n. The act of disinterring.
- dislodgement17n. The state or process of being dislodged.
- dismembering20n. The act or process whereby something is dismembered.
- dismissively21adv. In a dismissive manner.
- disobedience18n. Refusal to obey.
- disorganised15adj. Lacking order or organisation; confused; chaotic.
- disorganized24adj. Lacking order or organization; confused; chaotic.
- disorienting14adj. That causes disorientation; confusing.
- dispatchable22adj. Capable of being dispatched.
- dispensation15n. The act of dispensing or dealing out; distribution.
- displacement19n. The act of displacing, or the state of being displaced; a putting out...
- dispossessed16adj. Homeless.
- disputatious15adj. Of or relating to something that is in question as to its intent or...
- disqualifier25n. One who, or that which, disqualifies.
- disquisition22n. A methodical inquiry or investigation.
- disreputable17adj. Not respectable, lacking repute; discreditable.
- disruptively21adv. In a disruptive manner.
- dissatisfied17adj. Feeling or displaying disappointment or a lack of contentment.
- disseminated16adj. Spread around; widespread.
- disseminator15n. One who, or that which, disseminates.
- dissertation13n. A formal exposition of a subject, especially a research paper that...
- dissociation15n. The act of dissociating or disuniting; a state of separation; disunion.
- dissociative18adj. Removing or separating from some association.
- distillation13n. The act of falling in drops, or the act of pouring out in drops.
- distinctness15n. The property or degree of being distinct.
- distractedly19adv. In a distracted manner.
- distractible17adj. Capable of being distracted.
- distributary18adj. That distributes.
- distribution15n. An act of distributing or state of being distributed.
- distributism17n. An economic ideology, based on Catholic social teachings, according to...
- distributive18adj. Relating to distribution.
- districtwide19adj. Across an entire district.
- disturbingly19adv. In a disturbing manner.
- ditransitive16adj. Of a class of verbs which take both a direct and an indirect object. An...
- diversionary19adj. That serves as a diversion.
- diverticular18adj. Of or pertaining to the diverticulum.
- diverticulum20n. A small out-pouching of an organ wall such as the large intestine or...
- divertimento18n. Composition that has several short movements, a style that composers...
- divinization25n. The act or process of making divine.
- divisibility21n. The state of being divisible. The state capable of being divided.
- divisiveness19n. The characteristic of being divisive.
DO
- documentable19adj. Capable of being supported by documentary evidence.
- dodecahedral20adj. Having twelve plane surfaces.
- dodecahedron20n. A polyhedron with twelve faces; the regular dodecahedron has regular...
- dodecaphonic23adj. Of or pertaining to dodecaphony.
- dogmatically21adv. In a dogmatic manner.
- dolphinarium20n. An aquarium that houses dolphins.
- dolutegravir17n. An integrase inhibitor used to treat HIV infections.
- domestically20adv. In a domestic manner.
- domesticated18adj. Selectively bred to live with or around humans. (of an animal or a...
- dopaminergic20adj. Containing, involving, or transmitting dopamine; involving dopamine...
- doppelganger19n. A ghostly double of a living person, especially one that haunts such a...
- dorsiflexion23n. Flexion in the dorsal direction.
- dorsolateral13adj. Of, pertaining to, or situated on both the back and the side.
- dorsoventral16adj. Of, pertaining to, or situated at the back and front of something.
- downloadable19adj. Capable of being downloaded.
- downregulate17v. To decrease the number of cell receptors by using downregulation.
- downsampling21n. An instance of something being downsampled.
- downshifting23n. A social trend towards living a simpler, less ambitious life with a...
DR
- draftsperson18n. A draftsman or draftswoman.
- dragonslayer17n. One who slays a dragon.
- dramatically20adv. In a dramatic manner.
- dreamcatcher22n. A decorative Native American object in the form of a hoop and net with...
- drinkability22n. The state or property of being drinkable.
- dropshipping23n. A retail model where goods are sent directly from the supplier to the...
- drospirenone15n. A synthetic progestogen C₂₄H₃₀O₃ that is an analog of spironolactone...
DU
- dumbfounding22adj. Bewildering; astonishing.
DY
- dysautonomia18n. Any of a range of dysfunctions of the autonomic nervous system.
- dyslipidemia21n. An imbalance of lipids (especially cholesterol) in the blood...
- dysmenorrhea21n. Painful menstruation (menstrual pain), viewed as a symptom in any of...
1,628 rare twelve-letter words that start with D
- dacrocytosis
- dacryocystic
- dacryoplasty
- dactylectomy
- dactylically
- dactyliology
- dactylograph
- dactylogyrid
- dactylomancy
- dactylopodid
- dactyloscopy
- dactylospasm
- dactylostyle
- dactylozooid
- dalbergenone
- dalfopristin
- dalmanelloid
- damagingness
- damenization
- damkjernitic
- damnableness
- damnacanthal
- danceability
- dancerliness
- dandarabilla
- dandruffless
- dandrufflike
- dandyishness
- danofloxacin
- daphnandrine
- daraxonrasib
- daredevilish
- daredevilism
- daredeviltry
- darglitazone
- daridorexant
- darinaparsin
- darksomeness
- darlingtonia
- darmstadtium
- darolutamide
- dashkesanite
- dasiglucagon
- daspletosaur
- dasyphyllous
- dasyuromorph
- databaseless
- databaselike
- datafication
- datalessness
- dateaversary
- datelessness
- dativization
- daubentoniid
- daughtercard
- daughterhood
- daughterlang
- daughterless
- daughterlike
- daughterling
- daughterness
- daughtership
- dauntingness
- daydreamlike
- daynightmare
- dazzlingness
- deabbreviate
- deadaptation
- deadjectival
- deadlockable
- dealcoholize
- dealkylating
- dealkylation
- dealkylative
- dealuminated
- deambulation
- deambulatory
- deannexation
- dearomatized
- dearsenicate
- dearticulate
- deasphalting
- deaspiration
- deassimilate
- deastringent
- deathfulness
- deathmatcher
- deattenuated
- deazaguanine
- deazauridine
- debacchation
- debatability
- debilitative
- debituminize
- debonairness
- deboronation
- debottleneck
- debranchiate
- debrisoquine
- debrominated
- debtlessness
- debutyration
- decabrachian
- decacanthous
- decacarbonyl
- decachloride
- decacuminate
- decadienoate
- decaffeinate
- decaffeinize
- decafluoride
- decahydrated
- decalcifying
- decalcinated
- decalcomanie
- decalescence
- decalibrated
- decantherous
- decapacitate
- decapentenyl
- decapetalous
- decaphyllous
- decapitalize
- decarbonizer
- decasepalous
- decaspermous
- decastellate
- decasyllabic
- decasyllable
- decasyllabon
- decategorize
- decatenation
- decatenatory
- decatetraene
- decatungsten
- decavanadate
- decavitation
- decayability
- decelerative
- deceleratory
- decemcostate
- decemdentate
- decemlocular
- decempartite
- decemplicate
- decemvirship
- decensorship
- decentralism
- decentralist
- decentration
- deceptionism
- deceptionist
- deceptiously
- deceptitious
- decernotinib
- dechanneling
- dechlorinase
- dechlorinate
- dechorionate
- dechorionize
- decidophobia
- decidualized
- deciduogenic
- decimestrial
- decipherably
- decisionally
- decisionless
- decitizenize
- deckenkarren
- declaredness
- declassicize
- declassifier
- declenperone
- declensional
- declinometer
- declustering
- decocainized
- decodability
- decolonially
- decolourized
- decommitment
- decompactify
- decompaction
- decompensate
- decompilable
- decomplexant
- decomplexify
- decomplicate
- decomponible
- decomposited
- decompoundly
- decondensing
- deconflation
- decongestive
- deconsecrate
- decontrolled
- deconvoluted
- decoordinate
- decorability
- decorational
- decoronation
- decorousness
- decorrelated
- decorrelator
- decorticator
- decouplement
- decreaseless
- decrepitness
- decrustation
- decumulation
- dedecoration
- dedicational
- dedicatorial
- dedicatorily
- dedispersion
- dedolomitize
- dedoublement
- dedovshchina
- deducibility
- deduplicator
- deedlessness
- deepwaterman
- deethylation
- deetiolation
- deexcitation
- defactualize
- defamatorily
- defascistize
- defatigation
- defeatedness
- defecography
- defectionism
- defectionist
- defectoscope
- defectoscopy
- defectuosity
- defederalize
- defederation
- defemination
- defenderless
- defendership
- defensorship
- deferentitis
- deferoxamide
- defervescent
- defibrillize
- defibulation
- defiguration
- defiltration
- definiential
- definitorily
- deflagellate
- deflagrative
- deflatedness
- deflationism
- deflationist
- deflavinated
- deflectional
- deflocculant
- deflocculate
- deflowerment
- defluorinate
- deformedness
- deformylated
- defraudation
- defucosylate
- degelatinise
- degemination
- degeneralize
- degenerately
- degenerously
- degerminator
- deglottalize
- deglutitious
- degradedness
- degrammatize
- degranulator
- degravitator
- degressively
- degringolade
- dehalogenase
- dehalogenate
- dehegemonize
- dehydratable
- dehydroamino
- dehydroarene
- dehydrobenzo
- dehydrodimer
- dehydronated
- dehydrosugar
- deicticality
- deideologize
- deinacridine
- deinactivate
- deindexation
- deinfibulate
- deinfluencer
- deinitialize
- deinocheirid
- deinotheriid
The first 300 are shown.
Questions about these words
- How many twelve-letter words that start with D are there?
- Word.ws lists 277 twelve-letter words that start with D, plus 1,628 rare ones.
- What are common twelve-letter words that start with D?
- distribution, disappointed, developments, difficulties, deliberately, dramatically, differential and disciplinary.
- Which of the twelve-letter words that start with D has the highest letter score?
- dichotomized scores 30 points with the standard letter tile values.
Related word lists
Source and license
Word lists and meanings adapted from the Wiktionary entry of each word. Text available under the Creative Commons Attribution-ShareAlike 4.0 license. Word.ws left out names, abbreviations, misspellings and offensive words, and ordered the most common words by how often they appear in English (wordfreq). Meanings from Wiktionary; this is not an official Scrabble, Words With Friends or Wordle word list. Wiktionary data of 2026-09-02.
Cite this page: “12-Letter Words Starting with D: 277 Words.” Word.ws, https://word.ws/words/12-letter/starting-with-d. Based on Wiktionary, CC BY-SA 4.0.
