Word.ws English Dictionary

12-Letter Words Starting with O

There are 108 twelve-letter words that start with O on Word.ws, from objectifying to oxyacetylene. The most common are organization, occasionally, organisation, overwhelming and occupational.

Meanings from Wiktionary. Not an official Scrabble, Words With Friends or Wordle word list.

All 108 twelve-letter words that start with O

OB

  • objectifying30n. Objectification.
  • oblanceolate16adj. Of a reversed lanceolate shape: attached to the stem by the pointed...
  • obligatorily18adv. In an obligatory manner.
  • obliterating15adj. Causing obliteration; devastating.
  • obliteration14n. The total destruction of something.
  • obscurantism18n. A state of opposition to human progress or enlightenment.
  • obscurantist16n. A practitioner of obscurantism; an obscurant.
  • obsequiously26adv. In an obsequious manner.
  • obsolescence18n. The state of being obsolete—no longer in use; gone into disuse; disused...
  • obstetrician16n. A physician who specializes in childbirth.
  • obstreperous16adj. Attended by, or making, a loud and tumultuous noise; boisterous.

OC

  • occasionally19adv. On occasion: at relatively infrequent intervals, from time to time...
  • occupational18adj. Of, belonging, or relating to an occupation (in any sense).
  • oceanography23n. The exploration and scientific study of the oceans and ocean floor.
  • octogenarian15n. Synonym of eightysomething: a person between 80 and 89 years old.
  • octosyllabic21adj. Containing eight syllables.

OD

OF

  • officeholder24n. A person who holds an office, especially one appointed or elected to a...

OL

  • oligarchical20adj. Oligarchic.
  • oligopeptide18n. A peptide containing a relatively small number of amino acids.
  • oligospermia17n. Low concentration of sperm in semen.
  • oligotrophic20adj. Deficient in nutrition (providing little nourishment).

OM

  • ombudsperson19n. Synonym of ombudsman.
  • omnipresence18n. The ability to be, or the characteristic of being, at all places at the...
  • omnishambles21n. A situation that is bad or mismanaged in every way.

ON

  • onomatopoeia16n. The property of a word that sounds like what it represents.
  • onomatopoeic18adj. Of or relating to onomatopoeia.

OO

  • oophorectomy24n. The surgical removal of one or both ovaries, usually performed to treat...

OP

  • operatically19adv. In an operatic manner.
  • oppositional16adj. Of, pertaining to, or exhibiting opposition.
  • oppressively22adv. In an oppressive manner.
  • optimization25n. The design and operation of a system or process to make it as good as...
  • optogenetics17n. A science that combines optics and genetics, aiming at controlling...

OR

  • orchestrator17n. One who orchestrates.
  • orchidaceous20adj. Of or pertaining to orchids.
  • ordinariness13n. The quality or condition of being ordinary.
  • organisation13n. Non-Oxford British English and Australian standard spelling of...
  • organization22n. The quality of being organized.
  • organoleptic17adj. Of or pertaining to the sensory properties of a particular food or...
  • organosulfur16adj. Describing any of a series of derivatives of sulfur that have at least...
  • orienteering13n. The act of racing across unfamiliar place using a map and compass.
  • ornamentally17adv. In an ornamental way.
  • orthodontics18n. A specialty of dentistry concerned with correcting misalignment of...
  • orthodontist16n. An orthodontic dentist.
  • orthognathic21adj. Straight-jawed.
  • orthogonally19adv. In an orthogonal manner; perpendicularly; at right angles.
  • orthographic23adj. Of a projection used in maps, architecture etc., in which the rays are...
  • orthorhombic24adj. Having three unequal axes at right angles.

OS

  • oscilloscope18n. An electronic measuring instrument that creates a visible...
  • ossification17n. The normal process by which bone is formed.
  • ostentatious12adj. Of ostentation.
  • osteoblastic16adj. Of or pertaining to an osteoblast.
  • osteogenesis13n. The formation and development of bone.
  • osteological15adj. Of or relating to osteology.
  • osteomalacia16n. A softening of adult bones due to inadequate mineralization; the adult...
  • osteoporosis14n. A disease, occurring especially in women following menopause, in which...
  • osteoporotic16adj. Relating to osteoporosis.
  • osteosarcoma16n. A type of cancer of the bone.

OT

  • otherworldly22adj. Of, concerned with, or preoccupied with a world different from the...
  • otosclerosis14n. Sclerosis of the tissues of the labyrinth and middle ear.

OU

  • outlandishly19adv. In an outlandish manner.
  • outmanoeuvre17v. To perform manoeuvres or movements more successfully or better than; to...
  • outmigration15n. Synonym of emigration.
  • outplacement18n. The process of helping to find new employment for redundant workers...
  • outrageously16adv. In an outrageous manner; to an outrageous degree.
  • outstandings14n. Outstanding amounts; unpaid debts.
  • outstretched18adj. Extended or stretched out.
  • outstripping17n. The act or process of something being outstripped.

OV

OX

  • oxaloacetate21n. Any salt or ester of oxaloacetic acid.
  • oxoglutarate20n. Any salt or ester of oxoglutaric acid.
  • oxyacetylene27n. A mixture of oxygen and acetylene, which burns at a high temperature...
1,101 rare twelve-letter words that start with O

The first 300 are shown.

Questions about these words

How many twelve-letter words that start with O are there?
Word.ws lists 108 twelve-letter words that start with O, plus 1,101 rare ones.
What are common twelve-letter words that start with O?
organization, occasionally, organisation, overwhelming, occupational, optimization, overshadowed and overcrowding.
Which of the twelve-letter words that start with O has the highest letter score?
objectifying scores 30 points with the standard letter tile values.

Related word lists

Source and license

Word lists and meanings adapted from the Wiktionary entry of each word. Text available under the Creative Commons Attribution-ShareAlike 4.0 license. Word.ws left out names, abbreviations, misspellings and offensive words, and ordered the most common words by how often they appear in English (wordfreq). Meanings from Wiktionary; this is not an official Scrabble, Words With Friends or Wordle word list. Wiktionary data of 2026-09-02.

Cite this page: “12-Letter Words Starting with O: 108 Words.” Word.ws, https://word.ws/words/12-letter/starting-with-o. Based on Wiktionary, CC BY-SA 4.0.