chaperome
Syllables: cha·per·ome/ˈʃæpəɹəʊm/US/ˈʃæpəɹoʊm/
chaperome noun: all the proteins called chaperones that assist in the folding of misfolded proteins in an organism, and other functions.
Noun
chaperome (plural chaperomes)
- All the proteins called chaperones that assist in the folding of misfolded proteins in an organism, and other functions.
- The availability of chaperones and cochaperones for folding of cargo will be sensitive to the globalcellular pool that we now define as the chaperome, a general term to define the unique steady-state composition of chaperones and their regulators in a given cell type. It is well established that...2006 November 17, Xiaodong Wang et al., “Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis”, in Cell, volume 127, number 4, Cambridge, Mass.: Cell Press, →DOI...
- To date data exist to describe the organ-specific distribution and function of many chaperones, but less is known about their cell-type specificity and how this changes in response to different stressors. A systems view on the entire "chaperome" would be essential to understand chaperone function...2011, Andreas Wyttenbach, Shmma Quraishe, Joanne Bailey, Vincent O’Connor, “Molecular Chaperones in the Mammalian Brain: Regional Distribution, Cellular Compartmentalization and Synaptic...
Examples of chaperome in a sentence
- It is well established that the chaperome can be altered by multiple signaling pathways to accommodate cellular stress and misfolding load.2006 November 17, Xiaodong Wang et al., “Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis”, in Cell...
- A systems view on the entire "chaperome" would be essential to understand chaperone function under basal and stress conditions.2011, Andreas Wyttenbach, Shmma Quraishe, Joanne Bailey, Vincent O’Connor, “Molecular Chaperones in the Mammalian Brain: Regional...
- In another study, Brehme et al. have examined the chaperome in C. elegans and human.2020, Kun Wang, Yu Shang, Fei Dou, “Brain Aging: Hsp90 and Neurodegenerative Diseases”, in Zhao Wang, editor, Aging and Aging-related...
- Redundancy in the chaperome networks is evidenced in a number of large-scale investigations where individual chaperomes were either genetically deleted or pharmacologically inhibited.2020, Pengrong Yan, Tai Wang, Monica L. Guzman, Radu I. Peter, Gabriela Chiosis, “Chaperome Networks – Redundancy and Implications for...
Forms of chaperome
| plural | chaperomes |
|---|
Origin of chaperome
From chaperone + -ome (suffix indicating the complete whole of a class of substances for a species or an individual), coined by American biochemist Xiaodong Wang and his collaborators in a November 2006 article in Cell: see the quotation.
Words formed from chaperome
Questions about chaperome
- What does chaperome mean?
- Chaperome means all the proteins called chaperones that assist in the folding of misfolded proteins in an organism, and other functions.
- How do you use chaperome in a sentence?
- It is well established that the chaperome can be altered by multiple signaling pathways to accommodate cellular stress and misfolding load.
- What part of speech is chaperome?
- Chaperome is a noun.
- How do you pronounce chaperome?
- Chaperome is pronounced /ˈʃæpəɹəʊm/ (UK).
- What is the plural of chaperome?
- The plural of chaperome is chaperomes.
Words near chaperome in the dictionary
Source and license
Adapted from Wiktionary: chaperome (page history and authors). Text available under the Creative Commons Attribution-ShareAlike 4.0 license. Word.ws reformatted the entry and added links. Wiktionary data of 2026-09-02.
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Pronunciation audio from Wikimedia Commons, each file under its own free license: LL-Q1860 (eng)-I learned some phrases-chaperome.wav.
Cite this entry: “chaperome.” Word.ws, https://word.ws/chaperome. Based on Wiktionary, CC BY-SA 4.0.