chaperomes

Noun

chaperome (plural chaperomes)

1. All the proteins called chaperones that assist in the folding of misfolded proteins in an organism, and other functions.
   • The availability of chaperones and cochaperones for folding of cargo will be sensitive to the globalcellular pool that we now define as the chaperome, a general term to define the unique steady-state composition of chaperones and their regulators in a given cell type. It is well established that...2006 November 17, Xiaodong Wang et al., “Hsp90 Cochaperone Aha1 Downregulation Rescues Misfolding of CFTR in Cystic Fibrosis”, in Cell, volume 127, number 4, Cambridge, Mass.: Cell Press, →DOI...